Certainly, I was surprised that it doesn't make me uncomfortable (water disrupts the cell structure of memory foam mattresses, it completely wrecks them, so a waterproof mattress protector is really essential, especially if you have cats like ours that knock glasses of water over onto the mattress on a semi-regular basis), but I don't know if I sweat less? Sounds like it's a possibility. I had kind of been assuming it was the texture and noise of plastic that was bothering you, and this would at least deal with that.